Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.
説明 | PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1. |
ターゲット&IC50 | Aurora A:0.8 nM, Aurora B:5 nM |
分子量 | 474.48 |
分子式 | C23H25F3N6O2 |
CAS No. | 942487-16-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 47.5 mg/mL (100 mM)
Ethanol: 9.5 mg/mL (20 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PF-03814735 942487-16-3 Angiogenesis Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling Tyrosine Kinase/Adaptors Aurora Kinase VEGFR FAK FLT Trk receptor PF03814735 inhibit Inhibitor Vascular endothelial growth factor receptor PF 03814735 inhibitor