Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting oxidative stress, inflammation, and modulating T-cell polarization, and may be useful for research on sickle cell anemia.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 19,000 | |||
10 mg | 在庫あり | ¥ 30,500 | |||
25 mg | 在庫あり | ¥ 65,000 | |||
50 mg | 在庫あり | ¥ 104,000 | |||
100 mg | 在庫あり | ¥ 167,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 21,000 |
説明 | PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting oxidative stress, inflammation, and modulating T-cell polarization, and may be useful for research on sickle cell anemia. |
ターゲット&IC50 | PDE9A:12 nM |
別名 | PF 04447943, Edelinontrine, PF04447943 |
分子量 | 395.46 |
分子式 | C20H25N7O2 |
CAS No. | 1082744-20-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 39.55 mg/mL (100 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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PF-04447943 1082744-20-4 Metabolism PDE PF 04447943 Edelinontrine PF04447943 Inhibitor inhibitor inhibit