Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.
説明 | PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker. |
ターゲット&IC50 | PDE10A:13 mg/kg(ED50), PDE10A:4.6 nM |
In vivo | In mice, PQ-10 shows a region-specific increase in 2-DG uptake in the globus pallidus (equivalent to the outer part of the primate pallidus) and lateral habenula [1]. |
別名 | A844337, PQ 10, A-844337, A 844337 |
分子量 | 403.43 |
分子式 | C22H21N5O3 |
CAS No. | 927691-21-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (148.72 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PQ-10 927691-21-2 Metabolism PDE inhibit Phosphodiesterase (PDE) Phosphodiesterase 10A translational biomarker schizophrenia PDE10A A844337 glucose metabolism PQ10 PQ 10 Inhibitor psychiatric disorders A-844337 A 844337 inhibitor