store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, which induces degradation of endogenous SGK3.PROTAC SGK3 degrader-1 inhibits GDC0941-induced proliferation of cancer cells.CAS 번호5017-88-83-4
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | お問い合わせ | ¥ 110,000 |
5 mg | お問い合わせ | ¥ 224,500 |
25 mg | お問い合わせ | ¥ 523,500 |
50 mg | お問い合わせ | ¥ 682,000 |
1 mL * 10 mM (in DMSO) | お問い合わせ | ¥ 9,000 |
説明 | PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, which induces degradation of endogenous SGK3.PROTAC SGK3 degrader-1 inhibits GDC0941-induced proliferation of cancer cells.CAS 번호5017-88-83-4 |
In vitro | SGK3-PROTAC1 (0.3 μM) induces endogenous SGK3 degradation by 50% within 2 hours, with maximal degradation of 80% observed within 8 hours, accompanied by loss of phosphorylation of SGK3 substrate NDRG1[1]. |
別名 | SGK3-PROTAC1 |
分子量 | 1157.38 |
分子式 | C57H73FN10O11S2 |
CAS No. | 2381320-35-8 |
store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (69.12 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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PROTAC SGK3 degrader-1 2381320-35-8 Metabolism SGK PROTAC SGK3 degrader 1 PROTAC SGK-3 degrader-1 SGK3-PROTAC1 PROTAC SGK3 degrader1 Inhibitor inhibitor inhibit