Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
説明 | CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1. |
ターゲット&IC50 | CK1:6 μM(IC50), CK1:8.5 μM(Ki) |
別名 | CKI 7 2HCl, CKI-7 dihydrochloride, CKI7 2HCl, CKI 7 dihydrochloride, CKI7 dihydrochloride, CKI-7 2HCl |
分子量 | 358.67 |
分子式 | C11H14Cl3N3O2S |
CAS No. | 1177141-67-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/ml (181.23 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CKI-7 1177141-67-1 Cell Cycle/Checkpoint Cytoskeletal Signaling MAPK Metabolism PI3K/Akt/mTOR signaling Stem Cells CDK S6 Kinase Casein Kinase SGK ROCK Serum and glucocorticoid-regulated kinase inhibit nestin S6K Inhibitor CK1 CKI 7 2HCl CKI-7 dihydrochloride CKI 7 Ribosomal S6 Kinase (RSK) CKI7 CKI 7 Dihydrochloride differentiation Cyclin dependent kinase CKI7 2HCl neural CKI 7 dihydrochloride Serum-glucocorticoid regulated kinase S6K1 MSK1 CKI7 dihydrochloride Wnt CKI-7 Dihydrochloride CKI-7 2HCl βIII-tubulin Sox1 CKI7 Dihydrochloride inhibitor