Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).
説明 | PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM). |
ターゲット&IC50 | HDAC:1-10 μM (EC50) |
キナーゼ試験 | mTOR and PI3K Cellular Assays: Cellular IC50 values for mTOR are determined using p53?/? MEFs. Cells are treated with vehicle or increasing concentrations of Torin 2 for 1 h and then lyse. Phosphorylation of S6K1 Thr-389 is monitored by immunoblotting using a phospho-specific antibody. Meanwhile, cellular IC50 values for PI3Ka are determined based on phosphorylation of Akt Thr-308 in p53?/?/mLST8?/? MEFs or human PC3 cells expressing the S473D mutant of Akt1. |
別名 | NCH-51, Cpd 51 |
分子量 | 390.56 |
分子式 | C20H26N2O2S2 |
CAS No. | 848354-66-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (140.82 mM)
You can also refer to dose conversion for different animals. 詳細
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PTACH 848354-66-5 Chromatin/Epigenetic DNA Damage/DNA Repair Microbiology/Virology Proteases/Proteasome HIV Protease HDAC HIV-1 inhibit NCH-51 Cpd 51 HIV Inhibitor Histone deacetylases hyperacetylation NCH51 Anti-cancer p21WAF1/CIP1 Human immunodeficiency virus SAHA NCH 51 inhibitor