549
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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T24141 | HIV-1 Inhibitor 18A | HIV-1 Inhibitor-18A | HIV Protease |
HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates. | |||
T9039 | HIV-1 Nef-IN-1 | HIV Protease | |
HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM). | |||
TP1149 | HIV-1 Rev (34-50) | HIV-1 Rev 34-50,HIV-1 rev Protein (34-50) | HIV Protease |
HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity. HIV-1 Rev (34-50) is derived from the Rev-responsive element-binding domains of Rev in HIV-1. | |||
T67833 | HIV-1 inhibitor-54 | HIV Protease | |
HIV-1 inhibitor-54 is a potent HIV-1 inhibitor showing anti-HIV activity (EC50 : 32 nM) against WT HIV-1 (strain IIIB) x in MT-4 cells.HIV-1 inhibitor-54 can be used to study viral infections. | |||
T9854 | HIV-1 inhibitor-6 | 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo- | HIV Protease |
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication. | |||
T39729 | HIV Protease Substrate 1 | ||
HIV Protease Substrate 1 is a fluorogenic compound that offers insights into the enzymatic activity of HIV protease, making it a valuable tool for studying this aspect. | |||
T40719 | (Cys47)-HIV-1 tat Protein (47-57) | (Cys47)-HIV-1 tat Protein (47-57) | |
(Cys47)-HIV-1 tat Protein (47-57) possesses membrane translocation functionality and can serve as a surface derivatization agent for magnetic pharmaceuticals, thereby enhancing their uptake into specific target cells. | |||
T60742 | HIV-1 integrase inhibitor 8 | HIV Protease | |
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1]. | |||
TP1809 | TAT | HIV Protease | |
TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating pept... | |||
T11564 | HIV-1 inhibitor-3 | Others | |
HIV-1 inhibitor-3 is an HIV infection inhibitor. | |||
T11566 | HIV-1 integrase inhibitor | Others | |
Hiv-1 integrase inhibitor is an effective anti-HIV drug. | |||
T1883 | Des(benzylpyridyl) Atazanavi | HIV Protease | |
The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor. | |||
TP1776 | HIV-1 TAT 48-60 | ||
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. This is one of the cell-penetrating peptides generated from the human immunodeficient virus ... | |||
T11565 | HIV-1 integrase inhibitor 7 | Others | |
HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM). | |||
T11568 | HIV-1 integrase inhibitor 4 | Others | |
HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM). | |||
T11567 | HIV-1 integrase inhibitor 3 | Others | |
HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM). | |||
T9212 | IMB-301 | Others , HIV Protease | |
IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model. | |||
T15371 | Gardiquimod | TLR , HIV Protease | |
Gardiquimod is a TLR7/8 agonist. When used at concentrations below 10 μM, Gardiquimod specifically activates TLR7. Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells... | |||
T12715 | Reverse transcriptase-IN-1 | HIV Protease | |
T16276 | NBD-556 | HIV Protease | |
NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. | |||
T4182 | Lavendustin B | Tyrosinase , transporter , HIV Protease | |
Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75). | |||
T11465 | Lenacapavir | GS-6207 | Others , HIV Protease |
T8233 | BRD3308 | Apoptosis , HIV Protease , HDAC | |
BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK. | |||
T28578 | Ro24-7429 | Ro 24-7429,Ro-24-7429,Ro 247429 | HIV Protease |
Ro24-7429 is an effective and orally active antagonist of HIV-1 transactivator protein Tat and an inhibitor of a runt-related transcription factor 1. Ro24-7429 has anti-HIV, antifibrotic, and anti-inflammatory effects. | |||
T9063 | Clathrin-IN-1 | HIV Protease | |
Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research. | |||
T11538 | Hck-IN-1 | HIV Protease , Src , Hck | |
Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w... | |||
T6246 | Cobicistat | Tybost,GS-9350 | P450 , HIV Protease |
Cobicistat (GS-9350) is a carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which it is used in combination, for the treatment of ... | |||
T20062 | Thiamine disulfide | TDS,Daiomin,Algoneurina | HIV Protease , Endogenous Metabolite |
Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing... | |||
T6420 | BMS-707035 | HIV Protease | |
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2. | |||
T3199 | PTACH | NCH-51,Cpd 51 | HIV Protease , HDAC |
PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM). | |||
T9223 | RO-0335 | Reverse Transcriptase | |
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical is... | |||
T76502 | HIV-1, HIV-2 Protease Substrate | ||
HIV-1, HIV-2 Protease Substrate is a compound serving as the substrate for the proteases of both HIV-1 and HIV-2, featuring four residues that allow for conservative substitutions at the substrate binding sites of these ... | |||
T11281L | FGI-106 tetrahydrochloride | Virus Protease , HCV Protease , Influenza Virus , HIV Protease | |
T27030 | CK176 | HIV-1 inhibitor-34,HIV-1 inhibitor 34,CK 176,CK-176,HIV-1 inhibitor34 | |
CK176 is a capsid targeted inhibitor of HIV-1 replication. CK176 shows an 11-fold improvement over I-XW-053 in blocking HIV-1 replication in primary human peripheral blood mononuclear cells (PBMCs). | |||
T6255 | Bromosporine | Epigenetic Reader Domain , CDK | |
Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively. | |||
T63813 | HIV-1 inhibitor-39 | ||
HIV-1 inhibitor-39 is a potent inhibitor of HIV-1 (EC50>112.88 μM). HIV-1 inhibitor-39 has anti-RT (HIV-1 reverse transcriptase) effect (IC50: 15.75 μM). HIV-1 inhibitor-39 exhibits cytotoxicity against MT-4 cells (CC50:... | |||
T62010 | HIV-1 inhibitor-20 | ||
HIV-1 inhibitor-20 is a potent HIV-1 inhibitor. | |||
T63963 | HIV-1 inhibitor-14 | ||
HIV-1 inhibitor-14 is a potent, broad-spectrum inhibitor of HIV-1 non-nucleoside reverse transcriptase (RT) (IC50=0.14 μM for HIV-1 RT). HIV-1 inhibitor-14 inhibits both wild-type and drug-resistant HIV-1 strains (EC50: ... | |||
T63018 | HIV-1 inhibitor-43 | ||
HIV-1 inhibitor-43 is a potent inhibitor of HIV-1, acting on HIV-1 Y188L (EC50: 21.3 nM), K103N-Y181C (EC50: 6.2 nM), K103N (EC50< 0.7 nM) and Y181C (EC50< 0.7 nM). HIV-1 inhibitor-43 reduces the expression of HIV-1 RNA ... | |||
T62526 | HIV-1 inhibitor-8 | ||
HIV-1 inhibitor-8 is a potent, orally active, low toxicity HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-8 is capable of acting on WT HIV-1 reverse transcriptase (IC50: 0.081 μM). HIV-1 in... | |||
T62782 | HIV-1 inhibitor-34 | ||
HIV-1 inhibitor-34 (compound 5q) is a potent, selective HIV-1 inhibitor that acts on HIV-1 (EC50: 6.4 nM), MT-4 cells (CC50: 16 μM). HIV-1 inhibitor-34 can be used in AIDS research. | |||
T62319 | HIV-1 inhibitor-44 | ||
HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM). | |||
T62287 | HIV-1 inhibitor-42 | ||
HIV-1 inhibitor-42 (compound 5b) is a potent inhibitor of HIV-1 (IC50: 0.06 μM). HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase (IC50: 0.518 μM) and DNA-dependent DNA polymerase (IC50. 0.072 μM). | |||
T62690 | HIV-1 inhibitor-46 | ||
HIV-1 inhibitor-46 (compound 13d) is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (EC50: 1.425 μM). HIV-1 inhibitor-46 can be used in the study of AIDS. | |||
T61801 | HIV-1 inhibitor-35 | ||
HIV-1 inhibitor-35 (compound 74) is a highly potent inhibitor of the HIV-1 virus, exhibiting EC50 values of 80 nM and 70 nM for LTR and CMV, respectively, in HEK293 cells. Additionally, HIV-1 inhibitor-35 demonstrates in... | |||
T61797 | HIV-1 inhibitor-15 | ||
HIV-1 inhibitor-15 (compound 9d) is a potent and broad-spectrum inhibitor targeting HIV-1. It exhibits inhibitory activity against HIV-1 WT, L100I, K103N, Y181C, and E138K with respective EC50 values of 1.7 nM, 4 nM, 2 n... | |||
T78749 | HIV-1 inhibitor-57 | ||
HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficac... | |||
T61670 | HIV-1 inhibitor-38 | ||
HIV-1 inhibitor-38 (Compound 91) is a powerful agent that inhibits the activity of HIV-1. It exhibits great potential as a novel latency reversing agent, making it a promising candidate for further development [1]. | |||
T79324 | HIV-1 inhibitor-59 | ||
HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM. Additionally, it demonstrates moderate inhibitory activity against the rev... | |||
T63363 | HIV-1 inhibitor-19 | ||
HIV-1 inhibitor-19 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (NNRTI) that acts on L100I, K103N and V106A/F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5783 | Rosamultin | Antioxidant , HIV Protease | |
Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity. | |||
TN1103 | Diphyllin | ATPase , Proton pump , Influenza Virus , HIV Protease | |
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling. | |||
T6S2391 | L-Chicoric Acid | (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid | Others , HIV Protease |
L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ... | |||
T4962 | Zingibroside R1 | Ginsenoside Z-R1 | HIV Protease |
Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity. | |||
T22468 | 1-Deoxymannojirimycin hydrochloride | Others , Influenza Virus , HIV Protease | |
α-mannosidase I inhibitor | |||
T0200 | α-Lipoic Acid | Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid | Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite |
α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ... | |||
T4S1383 | Escin IA | Aescin IA,Escin IA;Aescin IA,Escin IA | HIV Protease |
Escin IA (Escin IA;Aescin IA) is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved ... | |||
T4S1718 | Punicalin | HBV , HIV Protease | |
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM). | |||
T3730 | Methyl gallate | NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin | Reactive Oxygen Species , HIV Protease , Reverse Transcriptase , Antibacterial |
Methyl gallate (Gallincin) is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities. | |||
T2S0223 | Isosinensetin | 6-Demethoxynobiletin | Antioxidant , HIV Protease , Antibacterial , P-gp |
1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities. | |||
T4S1387 | Isoescin IA | HIV Protease | |
Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. It has anti-HIV-1 protease activity. | |||
TN5263 | 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one | Xanthohumol | Apoptosis , BCL , PARP , HCV Protease , IAP , Caspase , HIV Protease , NMDAR , p53 |
1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) , prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus,is e... | |||
TN2283 | Tripterifordin | HIV Protease | |
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml. | |||
T3323 | Ursonic Acid | CCRIS 7123,NSC4060,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966 | Apoptosis , HIV Protease , Endogenous Metabolite |
Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor. | |||
T4S1521 | 1,4-Dicaffeoylquinic acid | HIV Protease | |
1,4-Dicaffeoylquinic acid has antioxidant activity.1,4-Dicaffeoylquinic acid is a potent and highly selective class of HIV-1 integrase inhibitors, inhibitsHIV-1 replication in MT-2 cell culture at non-toxic concentration... | |||
T5782 | Bevirimat | YK FH312,MPC-4326,PA-457 | HIV Protease |
Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation. | |||
TJS1779 | Protosappanin A | PTA | NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT |
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory ... | |||
T2S1158 | 4,5-Dicaffeoylquinic acid | 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C | Others , HBV , Endogenous Metabolite |
1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity. | |||
TL0006 | Cichoric Acid | Dicaffeoyltartaric acid,Chicoric Acid | Reactive Oxygen Species , HIV Protease |
Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ... | |||
T4537 | Cholic acid sodium | SodiumCholate | HIV Protease , Endogenous Metabolite |
Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity. | |||
T8689 | Chloroquine | CQ | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als... | |||
T4S0295 | Apigenin 7-glucoside | Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,Thalictiin,Apigetrin | Reactive Oxygen Species , HIV Protease |
1. Apigenin 7-glucoside (Cosmosiin) is a anti-HIV agent. 2. Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 tr... | |||
T2930 | α-Lipoic Acid | Lipoic acid,Alphalipoic acid | NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite |
α-Lipoic Acid (Alphalipoic acid) inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.α-Lipoic Acid is an antioxidant, which is an es... | |||
T6841 | Fumagillin | NSC9168,Amebacilin | Others , HIV Protease , Antibiotic , Parasite |
Fumagillin (Amebacilin) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. | |||
TN1059 | Ganoderic acid B | IL Receptor , HIV Protease , JAK , STAT | |
Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has an... | |||
T3122 | Fangchinoline | Tetrandrine B,(+)-Limacine,Hanfangichin B,(+)-Fangchinoline | Apoptosis , FAK , HIV Protease , Autophagy |
Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore. | |||
TN1622 | Ermanin | NOS , Influenza Virus , COX , HIV Protease , Antibacterial , Antibiotic | |
Ermanin is a flavonoid isolated from Tanacetum microphyllum.Ermanin inhibits platelet aggregation and has anti-tuberculosis and anti-viral/bacterial properties.Ermanin has anti-inflammatory activity by inhibiting the exp... | |||
T5S2017 | Ingenol | (-)-Ingenol | PKC |
1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV... | |||
TN1727 | Helichrysetin | Apoptosis , HIV Protease | |
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29. | |||
T4839 | Ac-Ala-OH | N-Acetylalanine,N-Acetyl-L-alanine | Others , Endogenous Metabolite |
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro... | |||
T5S1103 | Isoliensinine | Isoliensinin | Apoptosis , Antioxidant |
1. Isoliensinine (Isoliensinin), a natural phenolic bisbenzyltetrahydroisoquinoline alkaloid, has received considerable attention for its potential biological effects such as antioxidant and anti-HIV activities. 2. Isoli... | |||
T0474 | Erythromycin ethylsuccinate | EES | ribosome , HIV Protease , Antibacterial , Antibiotic , Autophagy |
Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus. | |||
T0966 | Sennoside A | NSC 112929 | MAO , HIV Protease |
Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine. | |||
T3321 | Oleanonic acid | 3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,3-Ketooleanolic Acid | HIV Protease |
Oleanonic acid (3-Ketooleanolic Acid) is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties. | |||
T5429 | Theaflavin 3,3'-digallate | 8-Gingerol,TFDG | Virus Protease , Antioxidant , HIV Protease , HSV |
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul... | |||
T16791 | Rottlerin | Mallotoxin,NSC 56346,NSC 94525 | CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy |
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase... | |||
T4S0797 | Berberine | Berberin,Umbellatine | Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy |
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3.... | |||
T2S0731 | Trilobatin | P-Phlorizin | Amylase |
Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory respon... | |||
T2830 | Betulinic acid | ALS-357,Lupatic acid,Betulic acid | Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy |
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert... | |||
T25445 | Ganoderiol B | ||
Ganoderiol B is a moderately active HIV-1 PR inhibitor (IC50: 0.17-0.23 mM). | |||
TN6541 | Cleomiscosin B | ||
Cleomiscosins A, B and C exhibit liver-protective properties. Cleomiscosin B shows the potent anti-HIV-1 activity in vitro and also has protective effects on MT4 cells infected by HIV-1(IIIB). | |||
TN4555 | Methyl salvionolate A | HIV Protease | |
Methyl salvionolate A has anti-HIV-1 activity. | |||
TN4820 | Pre-schisanartanin B | HIV Protease | |
Pre-schisanartanin B has cytotoxicity, it also has anti-HIV-1 activity. | |||
TN5675 | Ganomycin I | ||
Ganomycin I inhibits the activity of HIV-1 protease. | |||
TN5012 | Shizukaol C | HIV Protease , Antifection | |
1. Shizukaol C shows anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains. <br/> 2. Shizukaol C has significant cytotoxicities against C8166 cells. <br/> | |||
T79934 | Clavirolide L | ||
Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 without inhibiting the RT enzyme, making it a valuable agent for HIV infectio... | |||
T75553 | Salvianan A | ||
1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1]. | |||
T73758 | Glycolithocholic acid 3-sulfate | ||
Glycolithocholic acid 3-sulfate (SLCG), a cholic acid derivative and glycolithocholic acid metabolite, effectively inhibits HIV-1 replication in vitro. This compound holds potential for researching HIV infection and gall... | |||
TN4835 | Przewalskin | HIV Protease | |
Przewalskin A and Przewalskin B showed modest anti-HIV-1 activity with EC50 = 41 and 30 microg/mL, respectively. | |||
T80952 | Tremuloidin | ||
Tremuloidin (Compound 2), a salicylic acid derivative from Homalium cochinchinensis, exhibits weak activity against HIV-1 [1]. | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02882 | HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) | HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.2 kDa. | |||
TMPY-01373 | HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His) | HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is I6TSC9. | |||
TMPY-04192 | HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) | HIV | E. coli |
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P04591. | |||
TMPY-01552 | HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) | HIV | E. coli |
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is B6DRA0. | |||
TMPJ-01313 | HIV-1 gp120 Protein (His) | HIV | HEK293 Cells |
Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chai... | |||
TMPY-01408 | HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) | HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 98 kDa. | |||
TMPY-00426 | HIV-1 (group P, strain RBF168) gp140 Protein (hFc) | HIV | HEK293 Cells |
HIV-1 (group P, strain RBF168) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 99.4 kDa and the accession number is D0VTQ8. | |||
TMPY-04198 | HIV-1 (group O, strain BCF06) p24 Protein (His) | HIV | E. coli |
HIV-1 (group O, strain BCF06) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.6 kDa and the accession number is C7G2S7. | |||
TMPY-00427 | HIV-1 (group P, strain RBF168) gp120 Protein (His) | HIV | HEK293 Cells |
HIV-1 (group P, strain RBF168) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.2 kDa and the accession number is D0VTQ8. | |||
TMPY-01556 | HIV-1 (group N, strain 06CM-U14296) p24 protein (His) | HIV | E. coli |
HIV-1 (group N, strain 06CM-U14296) p24 protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27 kDa. | |||
TMPY-06486 | HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated | HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is AFM77980.1. | |||
TMPY-00425 | HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) | HIV | HEK293 Cells |
HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 97.4 kDa and the accession number is P90249. | |||
TMPY-04194 | HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His) | HIV | E. coli |
HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is O12157. | |||
TMPY-00316 | HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His) | HIV | HEK293 Cells |
HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is Q03805. | |||
TMPY-04915 | HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His) | HIV | HEK293 Cells |
HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is Q9YUL5. | |||
TMPY-04871 | HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) | HIV | HEK293 Cells |
HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 99.9 kDa and the accession number is O12164. | |||
TMPY-04196 | HIV-1 (group M, subtype D, strain NDK) p24 Protein (His) | HIV | E. coli |
HIV-1 (group M, subtype D, strain NDK) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P18800. | |||
TMPY-01558 | HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His) | HIV | HEK293 Cells |
HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.4 kDa. | |||
TMPY-00309 | HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His) | HIV | HEK293 Cells |
HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is O11407. | |||
TMPH-01520 | HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) | HIV-1 | E. coli |
HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.8 kDa and the accession number is P0C1P2. | |||
TMPH-01519 | HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc) | HIV-1 | E. coli |
HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.9 kDa and the accession number is O12160. | |||
TMPY-00302 | HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His) | HIV | HEK293 Cells |
HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.2 kDa and the accession number is Q6BC58. | |||
TMPY-01442 | DMBT1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d... | |||
TMPK-00896 | CCR8 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and ... | |||
TMPK-00897 | CCR8 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and ... | |||
TMPJ-00873 | CCL3L1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including che... | |||
TMPH-02300 | RAD23A Protein, Human, Recombinant (His) | Human | E. coli |
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chain... | |||
TMPH-01248 | ADAR Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio... | |||
TMPK-01316 | CCR8 Protein, Cynomolgus, Recombinant (mFc) | Cynomolgus | HEK293 Cells |
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and ... | |||
TMPY-03413 | PPIL2 Protein, Human, Recombinant (aa 280-457, His) | Human | E. coli |
PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosp... | |||
TMPJ-01330 | CD299 Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-S... | |||
TMPH-01065 | CCR4 Protein-VLP, Human, Recombinant (His) | Human | HEK293 Cells |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger... | |||
TMPH-01064 | CCR4 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger... | |||
TMPJ-01037 | CXCR4 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor ... | |||
TMPJ-00679 | SGTA Protein, Human, Recombinant (His) | Human | E. coli |
Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co... | |||
TMPY-03285 | PPIL1 Protein, Human, Recombinant (His) | Human | E. coli |
PPIL1 is a member of the cyclophilin family. Cyclophilins are well conserved and ubiquitous. Members of cyclophilin family take a significant part in protein folding, immunosuppression by cyclosporin A, and infection of ... | |||
TMPK-00668 | IL-21R Protein, Cynomolgus, Recombinant (aa 41-254, His) | Cynomolgus | HEK293 Cells |
IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by... | |||
TMPJ-00810 | ITGA5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In cas... | |||
TMPH-02212 | TLR8 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Endosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against pathogens through recognition of RNA degradation products specific to microorganisms that are initially proc... | |||
TMPJ-00394 | LDLR Protein, Human, Recombinant (Avi & His), Biotinylated | Human | HEK293 Cells |
Low-density lipoprotein receptor 9 (LDL receptor) is a single-pass type I membrane protein which belongs to the LDLR family. It contains 3 EGF-like domains, 7 LDL-receptor class A domains, and 6 LDL-receptor class B repe... | |||
TMPJ-01122 | KARS Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Lysine-tRNA ligase, also known as Lysyl-tRNA synthetase, LysRS, KARS and KIAA0070, belongs to the class-II aminoacyl-tRNA synthetase family. The N-terminal cytoplasmic domain (1-65) is a functional tRNA-binding domain, w... | |||
TMPY-00493 | IL-19 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the r... | |||
TMPJ-00831 | CCL3 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, ... | |||
TMPY-01711 | Serpin B2 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl... | |||
TMPY-00886 | MMP-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MMP1, also known as MMP-1, contains 4 hemopexin-like domains and is a member of the matrix metalloproteinase (MMP) family. Matrix metalloproteases, also called matrixins, are zinc-dependent endopeptidases that are the ma... | |||
TMPY-04451 | AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&... | |||
TMPY-03745 | CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03878 | Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 | CD3D & CD3E Heterodimer Protein, Human, Recombinant | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-02700 | BCL2 Protein, Human, Recombinant (His) | Human | E. coli |
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L1100 | Protease Inhibitor Library | 343 compounds | |
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening; | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; |