Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: hTRPV4 of 0.77 μM, mTRPV4 of 4.0 μM, and rTRPV4 of 4.1 μM). RN-1747 also antagonizes TRPM8 (IC50: 4 μM).
説明 | RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: hTRPV4 of 0.77 μM, mTRPV4 of 4.0 μM, and rTRPV4 of 4.1 μM). RN-1747 also antagonizes TRPM8 (IC50: 4 μM). |
ターゲット&IC50 | TRPV4 (human):0.77 μM(EC50), TRPM8:4 μM, TRPV4 (rat):4.1 μM(EC50), TRPV4 (mouse):4.0 μM(EC50) |
分子量 | 395.86 |
分子式 | C17H18ClN3O4S |
CAS No. | 1024448-59-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 75 mg/mL (189.46 mM)
You can also refer to dose conversion for different animals. 詳細
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RN-1747 1024448-59-6 Membrane transporter/Ion channel TRP/TRPV Channel TRP Channel RN1747 Inhibitor Transient receptor potential channels RN 1747 inhibit inhibitor