Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
説明 | SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models. |
ターゲット&IC50 | SHP2:0.07 μM, p-ERK:0.250 μM |
別名 | SHP099 free base, SHP 099, SHP-099 |
分子量 | 352.26 |
分子式 | C16H19Cl2N5 |
CAS No. | 1801747-42-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.5 mg/mL (15.61 mM)
You can also refer to dose conversion for different animals. 詳細
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SHP099 1801747-42-1 Apoptosis Metabolism PERK Phosphatase inhibit SHP099 free base SHP 099 Inhibitor SHP-099 inhibitor