Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells.
説明 | PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. |
ターゲット&IC50 | PRL3:0.9 μM (IC50) |
In vitro | PRL-3 inhibitor, in a dose-dependent fashion, blocked the dephosphorylation of DiFMUP by PRL-3 and strongly suppressed the activity of PRL-3 phosphatase in PRL-3 overexpressing DLD-1 colon tumor cells [DLD-1 (PRL-3)]. Also, PRL-3 inhibitor dose-dependently blocked the migration of DLD-1 (PRL-3) cells, however, it did not inhibit the proliferation of DLD-1(PRL-3) cells, suggesting that PRL-3 inhibitor significantly blocked cell immigration and invasion without cytotoxicity |
別名 | PRL-3 Inhibitor, BR-1 |
分子量 | 485.21 |
分子式 | C17H11Br2NO2S2 |
CAS No. | 893449-38-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (113.35 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PRL-3 Inhibitor I 893449-38-2 Metabolism Others Phosphatase cells PRL-3 Inhibitor Inhibitor PRL3 Inhibitor I invasion BR 1 BR1 inhibit BR-1 melanoma PRL 3 Inhibitor I B16F10 inhibitor