Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SK1-IN-1 is a potent inhibitor of sphingosine kinase 1 (SPHK1)(IC50 of 58 nM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | 約6-8 週間 | ¥ 83,500 |
25 mg | 約6-8 週間 | ¥ 333,000 |
50 mg | 約6-8 週間 | ¥ 434,000 |
100 mg | 約6-8 週間 | ¥ 643,000 |
ターゲット&IC50 | SPHK1:58 nM |
In vivo | SK1-IN-1 exhibits a considerable enhancement in intrinsic clearance, especially when assessed against human liver microsomes. Chosen for rat pharmacokinetic (PK) studies, it reveals moderate oral bioavailability alongside acceptable circulation half-lives. |
分子量 | 398.5 |
分子式 | C22H30N4O3 |
CAS No. | 1218816-71-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (250.94 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SK1-IN-1 1218816-71-7 GPCR/G Protein S1P Receptor SK-1-IN-1 SK1IN1 SK1 IN 1 Inhibitor inhibitor inhibit