Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent and selective antagonist of S1P2.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 17,500 | |||
5 mg | 在庫あり | ¥ 37,500 | |||
10 mg | 在庫あり | ¥ 66,500 | |||
25 mg | 在庫あり | ¥ 133,000 | |||
50 mg | 在庫あり | ¥ 191,500 | |||
100 mg | 在庫あり | ¥ 264,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 41,000 |
説明 | GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent and selective antagonist of S1P2. |
In vitro | GLPG2938 significantly prevents the S1P-mediated contraction at all tested concentrations[1]. |
In vivo | In all species ,GLPG2938 shows good pharmacokinetics, with long half-life,low clearance,and good bioavailability. |
別名 | 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea |
分子量 | 503.4 |
分子式 | C20H19F6N7O2 |
CAS No. | 2130996-00-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (119.19 mM)
You can also refer to dose conversion for different animals. 詳細
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GLPG2938 2130996-00-6 GPCR/G Protein S1P Receptor LPL Receptor Lysophospholipid Receptor GLPG 2938 fibrosis inhibit 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea GLPG-2938 selective pulmonary Inhibitor potent idiopathic inhibitor