Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SPD304 is a selective TNF-α inhibitor and blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 µM for inhibiting in vitro TNF receptor 1 binding to TNF-α.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
500 μg | 約 35 days | ¥ 17,500 |
1 mg | 約 35 days | ¥ 32,500 |
5 mg | 約 35 days | ¥ 129,500 |
10 mg | 約 35 days | ¥ 225,000 |
説明 | SPD304 is a selective TNF-α inhibitor and blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 µM for inhibiting in vitro TNF receptor 1 binding to TNF-α. |
ターゲット&IC50 | TNF-α:22 μM |
In vitro | SPD304 (2 μM) obviously rescues the survivability of aHSCs, reduces the production of lipid hydroxides, and increased intracellular GSH. The co-treatment of GA (75 μM) and SPD304 (2 μM), down-regulate TRADD almost 2-fold and p−RIP3 1.4−fold compared to GA alone and promotes caspase 8 activation [4]. |
分子量 | 547.61 |
分子式 | C32H32F3N3O2 |
CAS No. | 869998-49-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 24 mg/mL (43.83 mM), Sonication is recommended.
H2O: 18 mg/mL (32.87 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SPD304 869998-49-2 Apoptosis TNF TNF Receptor Tumor Necrosis Factor Receptor inhibit Inhibitor SPD 304 TNFR SPD-304 inhibitor