Powder: -20°C for 3 years | In solvent: -80°C for 1 year
STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).
説明 | STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively). |
ターゲット&IC50 | K562 cells:(EC50)9 μM, KU812 cells:5 μM(EC50) |
In vitro | STAT5-IN-2 (100 nM-50 µM) inhibits cell growth in KG1a and MV-4-11 cell lines with EC50 values of 2.6 µM and 3.5 µM, respectively. In K562, KU812, KG1a and MV-4-11 cells, STAT5-IN-2 (10 µM) induces apoptosis. In KG1a, MV-4-11 and KU812 cells, STAT5-IN-2 (10 µM) blocks the phosphorylation of STAT5[1]. |
分子量 | 397.51 |
分子式 | C26H27N3O |
CAS No. | 2111834-61-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (226.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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STAT5-IN-2 2111834-61-6 Apoptosis JAK/STAT signaling Stem Cells STAT STAT-5-IN-2 STAT5IN2 STAT5 IN 2 Inhibitor inhibitor inhibit