keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the corresponding Cx43 GJCs.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 22,500 | |||
5 mg | 在庫あり | ¥ 45,500 | |||
10 mg | 在庫あり | ¥ 77,500 | |||
25 mg | 在庫あり | ¥ 137,000 | |||
50 mg | 在庫あり | ¥ 195,500 | |||
100 mg | 在庫あり | ¥ 268,500 |
説明 | TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the corresponding Cx43 GJCs. |
In vivo | TAT-Gap19 acetate (1 mg/kg/day) showed significantly decreased collagen deposition, as well as lower amounts of α-SMA-positive cells area in mice subjected to treatment with 100-200 mg thioacetamide (TAA)/kg body weight for eight weeks[1]. In 4 months old C57Bl6 male mice, TAT-Gap19 acetate (i.v.; 55 mg/kg) produces significant immune signal in the brain 24 h later[2]. |
分子量 | 2703.25 |
分子式 | C119H212N46O26 |
CAS No. | TP2110L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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TAT-Gap19 acetate TP2110L Cytoskeletal Signaling Gap Junction Protein TAT Gap19 acetate TAT-Gap19 Acetate TATGap19 acetate Inhibitor inhibitor inhibit