keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 12,000 | |||
2 mg | 在庫あり | ¥ 17,500 | |||
5 mg | 在庫あり | ¥ 29,000 | |||
10 mg | 在庫あり | ¥ 45,000 | |||
25 mg | 在庫あり | ¥ 86,500 | |||
50 mg | 在庫あり | ¥ 127,000 | |||
100 mg | 在庫あり | ¥ 181,000 |
説明 | Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43. |
In vitro | Hemichannel inhibition is due to the binding of Gap19 to the C-terminus (CT) thereby preventing intramolecular CT-CL interactions.?The peptide inhibited Cx43 hemichannel unitary currents in both HeLa cells exogenously expressing Cx43 and acutely isolated pig ventricular cardiomyocytes.?Treatment with Gap19 prevented metabolic inhibition-enhanced hemichannel openings, protected cardiomyocytes against volume overload and cell death following ischemia/reperfusion in vitro and modestly decreased the infarct size after myocardial ischemia/reperfusion in mice in vivo[2]. |
分子量 | 1161.44 |
分子式 | C55H96N14O13 |
CAS No. | 1507930-57-5 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 5 mM
DMSO: Insoluble
You can also refer to dose conversion for different animals. 詳細
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Gap19 1507930-57-5 Cytoskeletal Signaling Gap Junction Protein myocardial cytoplasmic Cx40/pannexin-1 inhibit C-terminus Gap 19 hemichannel Inhibitor loop Gap-19 Cx43 channels connexin inhibitor