Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 555,500 |
50 mg | 約10-14 週間 | ¥ 730,000 |
100 mg | 約10-14 週間 | ¥ 987,000 |
説明 | TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM). |
ターゲット&IC50 | TBK1:100 nM, IKKε:100 nM |
In vitro | IKKε and TBK1 are serine/threonine kinases and are highly homologous to other IkB kinases (IKK-α and IKK-β). The two kinases play an integral role in the innate immune system. Double-stranded RNA viruses are recognized by Toll-like receptors 3 and 4 and RNA helicases RIG-1 and MDA-5, and lead to the activation of the TRIF-TBK1/IKKε-IRF3 signaling cascade, resulting in type I interferon. response. |
分子量 | 498.53 |
分子式 | C28H26N4O5 |
CAS No. | 2058264-32-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TBK1/IKKε-IN-1 2058264-32-5 NF-Κb IκB/IKK TBK1/IKKε IN 1 TBK1/IKKεIN1 TBK-1/IKKε-IN-1 Inhibitor inhibitor inhibit