Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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1 mg | 在庫あり | ¥ 27,000 | |||
5 mg | 在庫あり | ¥ 66,000 | |||
10 mg | 在庫あり | ¥ 103,000 | |||
25 mg | 在庫あり | ¥ 170,000 | |||
50 mg | 在庫あり | ¥ 226,500 | |||
100 mg | 在庫あり | ¥ 319,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 68,500 |
説明 | VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. |
ターゲット&IC50 | GIRK1/2:165 nM(EC50) , GIRK1/4:720 nM(EC50) |
In vivo | Reduced stress‐induced hyperthermia (SIH), a physiological test of anxiolytic efficacy in wild mice, but had no impact in and Kcnj3 (Girk1) ?/? mice. |
動物実験 | Animal Model:Male C57BL/6J mice, Kcnj3?/? siblings female and male C57BL/6J mice. Dosage:10 mg/kg; 30mg/kg. Administration:Intraperitoneal injection |
分子量 | 349.83 |
分子式 | C18H21ClFN3O |
CAS No. | 2126040-21-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (714.63 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
VU0810464 2126040-21-7 Membrane transporter/Ion channel Potassium Channel cells KcsA neuronal GIRK HPC VU 0810464 SAN VU-0810464 inhibit Inhibitor inhibitor