Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentrations up to 10 μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1. Displays similar potency to VU 590
説明 | VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentrations up to 10 μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1. Displays similar potency to VU 590 |
ターゲット&IC50 | ROMK:0.24 μM |
分子量 | 404.76 |
分子式 | C16H13ClN6O5 |
CAS No. | 1315380-70-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 16 mg/mL (39.53 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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VU591 hydrochloride 1315380-70-1 Membrane transporter/Ion channel Potassium Channel VU 591 VU 591 Hydrochloride inhibit neurological Kir1.1 Inhibitor VU-591 Hydrochloride VU-591 hydrochloride VU591 KcsA ROMK channel ROMK Inhibitor VU-591 VU591 Hydrochloride inhibitor