Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WAY-213613 hydrochloride is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC 50 of 85 nM. WAY-213613 hydrochloride inhibits EAAT1 and EAAT3 with IC50 values of 5 and 3.8 microM, respectively. WAY-213613 hydrochloride shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function and can be used for the research of central nervous system [1] [2].
説明 | WAY-213613 hydrochloride is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC 50 of 85 nM. WAY-213613 hydrochloride inhibits EAAT1 and EAAT3 with IC50 values of 5 and 3.8 microM, respectively. WAY-213613 hydrochloride shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function and can be used for the research of central nervous system [1] [2]. |
ターゲット&IC50 | EAAT2 (human):85 nM , EAAT1 (human):5 μM , EAAT3 (human):3.8 μM |
別名 | WAY-213613 hydrochloride (868359-05-1 free base) |
分子量 | 451.65 |
分子式 | C16H14BrClF2N2O4 |
CAS No. | 2450268-84-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 0.1 mg/mL (insoluble)
DMSO: 49 mg/mL (108.49 mM), Sonication and heating to 80℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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WAY-213613 hydrochloride 2450268-84-3 Metabolism transporter 868359-05-1 WAY-213613 Hydrochloride WAY 213613 Hydrochloride WAY-213613 hydrochloride (868359-05-1 free base) WAY213613 Hydrochloride WAY 213613 hydrochloride WAY213613 hydrochloride 868359-05-1 free base Inhibitor inhibitor inhibit