Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
説明 | WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold). |
ターゲット&IC50 | mTOR:9 nM |
別名 | WAY600 |
分子量 | 494.59 |
分子式 | C28H30N8O |
CAS No. | 1062159-35-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 2 mg/mL (4.04 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 22 mg/mL (44.48 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
WAY-600 1062159-35-6 Angiogenesis PI3K/Akt/mTOR signaling Tyrosine Kinase/Adaptors PI3K VEGFR Src mTOR WAY 600 inhibit WAY600 Inhibitor Mammalian target of Rapamycin inhibitor