Powder: -20°C for 3 years | In solvent: -80°C for 1 year
YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.
説明 | YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity. |
ターゲット&IC50 | HIV:8.4 μM |
In vitro | YYA-021 enhances the neutralization sensitivity of simian-human immunodeficiency virus (SHIV) carrying the envelope from the clade B clinical human immunodeficiency virus type 1 (HIV-1) isolate MNA. [1] |
In vivo | In rats and rhesus macaques, YYA-021 (i.v.) shows moderate half-lives, wide tissue distribution and relatively high distribution volumes. [2] |
別名 | YYA 021 |
分子量 | 317.43 |
分子式 | C18H27N3O2 |
CAS No. | 144217-65-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (157.52 mM), Sonication is recommended.
H2O: < 0.1 mg/mL (insoluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
YYA-021 144217-65-2 Immunology/Inflammation Microbiology/Virology Proteases/Proteasome HIV Protease gp120/CD4 Human immunodeficiency virus inhibit YYA021 Inhibitor YYA 021 HIV inhibitor