Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 15,000 | |||
2 mg | 在庫あり | ¥ 22,500 | |||
5 mg | 在庫あり | ¥ 48,000 | |||
10 mg | 在庫あり | ¥ 80,000 | |||
25 mg | 在庫あり | ¥ 132,500 | |||
50 mg | 在庫あり | お問い合わせ | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 45,000 |
説明 | Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity. |
ターゲット&IC50 | PKCδ:0.376 nM (Ki), PKCα:0.3 nM (Ki), PKCγ:0.162 nM (Ki), PKCε:0.171 nM (Ki), PKCβ:0.105 nM (Ki) |
植物由来 |
別名 | Ingenol 3-Angelate, PEP005 |
分子量 | 430.53 |
分子式 | C25H34O6 |
CAS No. | 75567-37-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (209 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Ingenol mebutate 75567-37-2 Chromatin/Epigenetic Cytoskeletal Signaling Immunology/Inflammation Microbiology/Virology Proteases/Proteasome PKC HIV Protease gp120/CD4 Ingenol 3-Angelate PEP 005 PEP005 PEP-005 Inhibitor inhibitor inhibit