keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 9,000 |
5 mg | 在庫あり | ¥ 20,500 |
10 mg | 在庫あり | ¥ 34,000 |
25 mg | お問い合わせ | ¥ 68,500 |
50 mg | お問い合わせ | ¥ 112,000 |
100 mg | お問い合わせ | ¥ 163,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 31,500 |
説明 | Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM. |
ターゲット&IC50 | αvβ3 integrin:20 nM |
In vitro | Cyclo(RGDyK) shows high affinity and selectivity for αVβ3 over αVβ5 and αIIbβ3. [1] Cyclo(RGDyK)-conjugated micelles (TPM) facilitated the cell-specific uptake of DiI into B16-F10 cells and HUVECs via integrin-mediated endocytosis compared with Cyclo(RGDyK) -free micelles (NPM). [2] |
In vivo | In apoE?/? mice, Cyclo(RGDyK) (1 nmol, i.v.) inhibits the increase of αVβ3 integrin expression in the intima of the left stenotic carotid artery. [2] |
別名 | Cyclo(RGDyK) |
分子量 | 847.72 |
分子式 | C31H43F6N9O12 |
CAS No. | 250612-42-1 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 130 mg/mL(153.35 mM)
You can also refer to dose conversion for different animals. 詳細
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Cyclo(RGDyK) trifluoroacetate 250612-42-1 Cytoskeletal Signaling Integrin Cyclo(RGDyK) Trifluoroacetate inhibit Cyclo(RGDyK) Inhibitor inhibitor