keep away from moisture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 40,000 | |||
5 mg | 在庫あり | ¥ 98,500 | |||
10 mg | 在庫あり | ¥ 175,500 | |||
25 mg | 在庫あり | ¥ 358,000 | |||
50 mg | 在庫あり | ¥ 484,500 | |||
100 mg | 在庫あり | ¥ 672,500 |
説明 | γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage. |
ターゲット&IC50 | β-amyloid(42):0.37 nM, Notch:0.24 nM, β-amyloid(40):0.24 nM |
In vitro | At a concentration of 50 μM, compound E reduces the proliferation of T47D and MCF-7 cell lines by less than 50% [2]. |
別名 | Compound E |
分子量 | 490.5 |
分子式 | C27H24F2N4O3 |
CAS No. | 209986-17-4 |
keep away from moisture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (163.10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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γ-Secretase-IN-1 209986-17-4 Neuroscience Proteases/Proteasome Stem Cells Gamma-secretase Beta Amyloid Compound E Inhibitor inhibitor inhibit