Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, a valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 9,000 | |||
2 mg | 在庫あり | ¥ 12,500 | |||
5 mg | 在庫あり | ¥ 20,500 | |||
10 mg | 在庫あり | ¥ 35,500 | |||
25 mg | 在庫あり | ¥ 80,000 | |||
50 mg | 在庫あり | ¥ 119,000 | |||
100 mg | 在庫あり | ¥ 172,000 |
説明 | ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, a valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound. |
In vivo | The ALZ-801: Tramiprosate ratio in plasma and brain is 1.8 and 3.1, respectively in male CD-1 mice[1]. ALZ-801 (oral administration; 172 mg/kg; single dose) shows average AUCt values of 58,758 and 5841 ng/ml.h in plasma and brain, respectively. |
別名 | Valiltramiprosate |
分子量 | 238.3 |
分子式 | C8H18N2O4S |
CAS No. | 1034190-08-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 250 mg/mL (1049.10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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ALZ-801 1034190-08-3 Neuroscience Beta Amyloid β-amyloid peptide Alzheimer Amyloid-β Tramiprosate disease inhibit Abeta ALZ801 β-amyloid Valiltramiprosate Inhibitor ALZ 801 inhibitor