Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CWI1-2 HCL is an effective IGF2BP2 inhibitor, which can induce apoptosis and differentiation by binding IGF2BP2 and inhibiting its interaction with M6A-modified target transcription, and has therapeutic effects on leukemia.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 12,000 | |||
5 mg | 在庫あり | ¥ 28,500 | |||
10 mg | 在庫あり | ¥ 43,500 | |||
25 mg | 在庫あり | ¥ 85,000 | |||
50 mg | 在庫あり | ¥ 124,500 | |||
100 mg | 在庫あり | ¥ 177,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 36,500 |
説明 | CWI1-2 HCL is an effective IGF2BP2 inhibitor, which can induce apoptosis and differentiation by binding IGF2BP2 and inhibiting its interaction with M6A-modified target transcription, and has therapeutic effects on leukemia. |
In vitro | CWI1-2 (0-1 μM, 24 h) hydrochloride exhibits significant anti-leukemia efficacy.[1] |
In vivo | CWI1-2 (5 mg/kg, i.v., once daily, 7-10 days) hydrochloride significantly delays the onset of leukemia and prolongs the survival time in BMT recipient B6.SJL (CD45.1) mice, without significant impact on body weight.[1] |
分子量 | 556.23 |
分子式 | C22H18Cl4N6O3 |
CAS No. | 2408590-37-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (40.45 mM)
You can also refer to dose conversion for different animals. 詳細
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CWI1-2 HCL 2408590-37-2 Apoptosis CWI12HCL Inhibitor inhibitor inhibit