Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CB2R PAM is an orally active cannabinoid type 2 receptor (CB2Rs) positive mutational modulator that enhances CP 55940 and 2-Arachidonylglycerol-stimulated [35S]GTPγS binding to CB2 receptors, but has no effect in the absence of agonists. ...CB2R PAM shows anti-injury activity in a mouse model of neuropathic pain.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 12,000 | |||
5 mg | 在庫あり | ¥ 28,000 | |||
10 mg | 在庫あり | ¥ 41,000 | |||
25 mg | 在庫あり | ¥ 68,000 | |||
50 mg | 在庫あり | ¥ 103,000 | |||
100 mg | 在庫あり | ¥ 151,500 | |||
500 mg | 在庫あり | ¥ 317,000 |
説明 | CB2R PAM is an orally active cannabinoid type 2 receptor (CB2Rs) positive mutational modulator that enhances CP 55940 and 2-Arachidonylglycerol-stimulated [35S]GTPγS binding to CB2 receptors, but has no effect in the absence of agonists. ...CB2R PAM shows anti-injury activity in a mouse model of neuropathic pain. |
In vitro | CB2R Positive Allosteric Modulator (PAM) at a concentration of 100 nM notably enhances the capability of CP55940 and 2-AG, without affecting AEA, in promoting [35S]GTPγS binding to CB2 receptors.[1] |
In vivo | CB2R PAM (1-20 mg/kg; p.o.) displays antinociceptive activity.[1] |
別名 | Ec2la |
分子量 | 435.33 |
分子式 | C21H24BrFN2O2 |
CAS No. | 2244579-87-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45.0 mg/mL (103.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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CB2R PAM 2244579-87-9 GPCR/G Protein Cannabinoid Receptor Ec2la Inhibitor inhibitor inhibit