store at low temperature
store at -80°C
Farletuzumab (MORAb-003) is a potent inhibitor of folate receptor-α (FRα). Farletuzumab is a humanized monoclonal antibody with a high affinity for FRα. Farletuzumab inhibits the growth of cells that overexpress FRα. Farletuzumab can be used to study cancer.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 85,500 |
5 mg | 在庫あり | ¥ 214,500 |
10 mg | 在庫あり | ¥ 342,000 |
25 mg | 在庫あり | ¥ 503,000 |
50 mg | 在庫あり | ¥ 682,000 |
100 mg | 在庫あり | ¥ 902,000 |
説明 | Farletuzumab (MORAb-003) is a potent inhibitor of folate receptor-α (FRα). Farletuzumab is a humanized monoclonal antibody with a high affinity for FRα. Farletuzumab inhibits the growth of cells that overexpress FRα. Farletuzumab can be used to study cancer. |
In vitro |
In CHO-FR cells, Farletuzumab (MORAb-003; 0-10 µg/mL) inhibits FRα-dependent cell growth and increases folate EC50 in a dose-dependent manner[1]. In IGROV-1 cells (0.1-100 µg/mL; 1 h), Farletuzumab mediates tumor cytotoxicity in vitro through complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC)[1]. In CHO-FR cells (0-10 µg/mL), Farletuzumab inhibits the phosphorylation of proteins by Lyn kinase, a member of the src family of kinases, thereby blocking an FRα-mediated signaling pathway[1]. |
別名 | MORAb-003 |
分子量 | N/A |
CAS No. | 896723-44-7 |
store at low temperature
store at -80°C
You can also refer to dose conversion for different animals. 詳細
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Farletuzumab 896723-44-7 Cell Cycle/Checkpoint Antifolate MORAb-003 Inhibitor inhibitor inhibit