Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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5 mg | 在庫あり | ¥ 13,000 | |||
10 mg | 在庫あり | ¥ 20,500 | |||
25 mg | 在庫あり | ¥ 36,500 | |||
50 mg | 在庫あり | ¥ 60,500 | |||
100 mg | 在庫あり | ¥ 91,500 | |||
500 mg | 在庫あり | ¥ 209,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity. |
In vivo | In mammals, histamine N-methyltransferase (HMT) is the sole enzyme responsible for degrading histamine in the brain.?Metoprine, one of the most potent HMT inhibitors, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT.?Consequently, this compound can be a candidate for a prototype of drugs for the treatment of METH overdose[1]. |
分子量 | 269.13 |
分子式 | C11H10Cl2N4 |
CAS No. | 7761-45-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4 mg/mL (14.86 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Metoprine 7761-45-7 Cell Cycle/Checkpoint Chromatin/Epigenetic GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor Antifolate Histone Methyltransferase Inhibitor histamine HMT barrier antitumor N-methyltransferase diaminopyrimidine inhibit BW 197U blood-brain inhibitor