Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | お問い合わせ | ¥ 45,000 |
5 mg | お問い合わせ | ¥ 100,500 |
10 mg | お問い合わせ | ¥ 150,500 |
25 mg | お問い合わせ | ¥ 270,500 |
50 mg | お問い合わせ | ¥ 406,000 |
100 mg | お問い合わせ | ¥ 609,000 |
200 mg | お問い合わせ | ¥ 913,000 |
1 mL * 10 mM (in DMSO) | お問い合わせ | ¥ 102,500 |
説明 | GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models. |
In vitro | GLL398 exhibits a strong dose-dependent binding profile for the estrogen receptor with a Y537S point mutation with an IC50 of 29.5 nM[1]. |
分子量 | 398.26 |
分子式 | C25H23BO4 |
CAS No. | 2077980-80-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 245 mg/mL (615.18 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GLL 398 2077980-80-2 Endocrinology/Hormones Estrogen Receptor/ERR mutant inhibit ESR1 Y537S selective estrogen receptor degrader GLL-398 GLL398 Inhibitor SERD breast cancer inhibitor