Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 9,500 | |||
100 mg | 在庫あり | ¥ 15,500 | |||
200 mg | 在庫あり | ¥ 21,500 | |||
500 mg | 在庫あり | ¥ 36,500 |
説明 | HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1]. |
In vitro | HIV-1 integrase inhibitor 8 were tested against 3′-processing (TC) and strand-transfer (ST) activities in the presence of Mn2+ as the cationic cofactor by gel assay, IC50=275μM and 231μM, respectively. HIV-1 integrase inhibitor 8 were retested using Mg2+ and the IC50 of against strand-transfer (ST) activities was 200μM. HIV-1 integrase inhibitor 8 inhibits MCV topoisomerase and DNA religation with IC50 of 500 µM and 200 µM, respectively. HIV-1 integrase inhibitor 8 induces cell cytotoxicity with LD50 of 20 μM in HeLa cells[1]. |
分子量 | 308.41 |
分子式 | C21H24O2 |
CAS No. | 1568-80-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (145.91 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
HIV-1 integrase inhibitor 8 1568-80-5 Microbiology/Virology Proteases/Proteasome HIV Protease Inhibitor inhibitor inhibit