Powder: -20°C for 3 years | In solvent: -80°C for 1 year
icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 66,500 |
5 mg | 在庫あり | ¥ 152,500 |
10 mg | 在庫あり | ¥ 213,500 |
25 mg | 在庫あり | ¥ 301,000 |
50 mg | 在庫あり | ¥ 376,500 |
100 mg | 在庫あり | ¥ 458,000 |
説明 | icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases. |
In vitro | icFSP1(5 µM) triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1]. |
In vivo | In a tumour-bearing mouse model, icFSP1(i.p.) significantly inhibited tumour growth and decreased tumour weight, without affecting body weight. icFSP1 markedly increased the abundance of hFSP1 condensates and immunoreactivity to 4-hydroxynonenal, a lipid peroxidation breakdown product[1]. |
分子量 | 459.49 |
分子式 | C26H25N3O5 |
CAS No. | 1115910-36-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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icFSP1 1115910-36-5 Apoptosis Inhibitor inhibitor inhibit