Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JG-231 is a JG-98 analog with anticancer activity.JG-231 inhibits the MDA-MB-231 xenograft tumor model of triple-negative breast cancer (TNBC).JG-231 inhibits the interaction of Hsp70-BAG3.JG-231 inhibits the MDA-MB-231 xenograft tumor model of triple-negative breast cancer (TNBC). JG-231 inhibits MDA-MB-231 xenograft tumor model of triple negative breast cancer (TNBC).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 29,000 | |||
5 mg | 在庫あり | ¥ 72,000 | |||
10 mg | 在庫あり | ¥ 118,000 | |||
25 mg | 在庫あり | ¥ 195,000 | |||
50 mg | 在庫あり | ¥ 268,500 | |||
100 mg | 在庫あり | ¥ 363,000 | |||
500 mg | 在庫あり | ¥ 727,500 |
説明 | JG-231 is a JG-98 analog with anticancer activity.JG-231 inhibits the MDA-MB-231 xenograft tumor model of triple-negative breast cancer (TNBC).JG-231 inhibits the interaction of Hsp70-BAG3.JG-231 inhibits the MDA-MB-231 xenograft tumor model of triple-negative breast cancer (TNBC). JG-231 inhibits MDA-MB-231 xenograft tumor model of triple negative breast cancer (TNBC). |
In vivo | JG-231 (2, 4 mg/kg; administered intraperitoneally) effectively suppressed the growth of A375, A375-PLX/R, and Colo829 xenografts in athymic nude mice without causing significant body weight loss. JG231-treated tumors exhibited increased lamin A cleavage and p21CIP1 expression. Moreover, JG231-treated tumors also exhibited increased MEK1/2 phosphorylation.[3] |
分子量 | 619.47 |
分子式 | C22H18BrCl2N3OS4 |
CAS No. | 1627126-59-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1.8 mg/mL (2.9 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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JG-231 1627126-59-3 Cytoskeletal Signaling Metabolism HSP JG231 AVE8063. JG 231 AVE 8063 Inhibitor inhibitor inhibit