Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons.
説明 | KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons. |
ターゲット&IC50 | LOX1:19 μM |
In vitro |
KKII5 (100 μM) has a significant inhibitory effect on lipid peroxidation, with an inhibition rate of 98%.[1] KKII5 interacts with HIS499 of the cavity by forming a π-π stacking interaction between the benzene ring of the molecule and the imidazole ring of HIS499.[1] |
分子量 | 266.36 |
分子式 | C16H14N2S |
CAS No. | 6381-55-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 53.27 mg/mL (200 mM)
You can also refer to dose conversion for different animals. 詳細
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KKII5 6381-55-1 Metabolism Lipoxygenase Inhibitor inhibitor inhibit