store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LQZ-7F is a small molecule survivin dimerisation inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation, mitotic arrest, and apoptosis, and blocks human tumour growth in mouse xenograft assays.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 111,000 | |||
10 mg | 在庫あり | ¥ 159,000 | |||
25 mg | 在庫あり | ¥ 248,000 | |||
50 mg | 在庫あり | ¥ 342,000 | |||
100 mg | 在庫あり | ¥ 452,500 | |||
500 mg | 在庫あり | ¥ 902,000 |
説明 | LQZ-7F is a small molecule survivin dimerisation inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation, mitotic arrest, and apoptosis, and blocks human tumour growth in mouse xenograft assays. |
In vitro | LQZ-7F and LQZ-7F1 treatment at 2.5 μM for 72 hours inhibited the viability of prostate cancer cell lines PC-3 and C4-2, as determined by MTT assay. |
In vivo | LQZ-7F was administered at 25 mg/kg via intraperitoneal injection once every 3 days for a total of 8 treatments. On the 30th day after treatment, it was found to inhibit the growth of xenograft tumors[1]. |
分子量 | 349.26 |
分子式 | C14H7N9O3 |
CAS No. | 354543-09-2 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2 mg/mL (5.73 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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LQZ-7F 354543-09-2 Apoptosis Survivin Inhibitor inhibitor inhibit