keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Polyporenic acid C shows inhibitory activity against human collagenase.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 34,000 | |||
5 mg | 在庫あり | ¥ 87,000 | |||
10 mg | 在庫あり | ¥ 128,000 | |||
25 mg | 在庫あり | ¥ 203,500 | |||
50 mg | 在庫あり | ¥ 273,500 | |||
100 mg | 在庫あり | ¥ 363,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 98,500 |
説明 | Polyporenic acid C shows inhibitory activity against human collagenase. |
In vitro | Polyporenic acid C (PPAC) significantly reduced cell proliferation via induction of apoptosis as evidenced by sub-G1 analysis, annexin V-FITC staining, and increase in cleavage of procaspase-8, -3, and poly(ADP-ribose)-polymerase (PARP). However, unlike our previously reported lanostane-type triterpenoid, pachymic acid, treatment of cells with PPAC was not accompanied by disruption of mitochondrial membrane potential and increase in cleavage of procaspase-9. Further, PPC-induced apoptosis was inhibited by caspase-8 and pan-caspase inhibitors but not by a caspase-9 inhibitor. |
植物由来 |
分子量 | 482.69 |
分子式 | C31H46O4 |
CAS No. | 465-18-9 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (124.3 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Polyporenic acid C 465-18-9 Apoptosis Chromatin/Epigenetic DNA Damage/DNA Repair PI3K/Akt/mTOR signaling Proteases/Proteasome Caspase PI3K PARP cell inhibit Inhibitor lung cancer NSCLC inhibitor