Powder: -20°C for 3 years | In solvent: -80°C for 1 year
M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.M3541 prevents activation of DNA damage checkpoints, inhibits DNA damage repair, contributes to apoptosis, and induces death of ATM overexpressing tumor cells.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 119,000 |
5 mg | 在庫あり | ¥ 268,500 |
25 mg | 在庫あり | ¥ 441,000 |
50 mg | 在庫あり | ¥ 546,500 |
100 mg | 在庫あり | ¥ 711,500 |
説明 | M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.M3541 prevents activation of DNA damage checkpoints, inhibits DNA damage repair, contributes to apoptosis, and induces death of ATM overexpressing tumor cells. |
分子量 | 428.42 |
分子式 | C23H17FN6O2 |
CAS No. | 1360628-91-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1mg/ml, Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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M3541 1360628-91-6 Apoptosis DNA Damage/DNA Repair PI3K/Akt/mTOR signaling ATM/ATR M 3541 M-3541 BI-665915 BI 665915 Inhibitor inhibitor inhibit