Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson's disease model.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 10,500 | |||
2 mg | 在庫あり | ¥ 15,000 | |||
5 mg | 在庫あり | ¥ 24,500 | |||
10 mg | 在庫あり | ¥ 37,500 | |||
25 mg | 在庫あり | ¥ 66,500 | |||
50 mg | 在庫あり | ¥ 98,500 | |||
100 mg | 在庫あり | ¥ 136,000 | |||
500 mg | 在庫あり | ¥ 291,500 |
説明 | MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson's disease model. |
ターゲット&IC50 | MAO-A:37 nM (IC50), MAO-B:57 nM (IC50) |
In vitro | MAO-IN-M30 (0.25 nM; 72 hours) significantly increased cell viability to ~90% after exposure to Dexamethasone. MAO-IN-M30 treatment significantly decreases the occurrence of fragmented DNA compared to the dexamethasone-treated group in SH-SY5Y cells[3]. MAO-IN-M30 (0-10 μM; 24 hours) enhances PC12 cell survival[4]. |
In vivo | MAO-IN-M30 (0.5-2.5 mg/kg; p.o.; once daily for 14 consecutive days) possesses neuroprotective activities[6]. |
別名 | M 30 dihydrochloride |
分子量 | 299.2 |
分子式 | C14H16Cl2N2O |
CAS No. | 64821-19-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1.8 mg/mL (6 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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MAO-IN-M30 dihydrochloride 64821-19-8 Neuroscience Monoamine Oxidase M 30 Dihydrochloride M 30 dihydrochloride M 30 MAO-IN-M30 M-30 Dihydrochloride M30 M-30 MAO-IN-M30 Dihydrochloride M30 Dihydrochloride Inhibitor inhibitor inhibit