Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MAT2A-IN-10 (Compound 28), an orally active inhibitor of MAT2A, exhibits an IC50 of 26 nM and is utilized in cancer research [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | お問い合わせ | ¥ 314,500 |
50 mg | お問い合わせ | ¥ 638,000 |
100 mg | お問い合わせ | ¥ 849,500 |
説明 | MAT2A-IN-10 (Compound 28), an orally active inhibitor of MAT2A, exhibits an IC50 of 26 nM and is utilized in cancer research [1]. |
In vitro | MAT2A-IN-10 (Compound 28; 0.1 nM-10 μM; 4 days) inhibits the proliferation of HCT-116 (MTAP-/-) cells with an IC50 of 75 ± 5 nM, without affecting the proliferation of HCT-116 (WT) cells [1]. |
In vivo | MAT2A-IN-10 (Compound 28; orally; once daily for 6 days) induced tumor regression in the HCT-116 (MTAP-/-) mouse xenograft model [1]. |
分子量 | 534.51 |
分子式 | C27H24F2N6O4 |
CAS No. | 2924825-23-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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MAT2A-IN-10 2924825-23-8 Chromatin/Epigenetic Methionine Adenosyltransferase (MAT) Inhibitor inhibitor inhibit