Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the liver, nasal cavity, trachea, lung and esophagus.
説明 | N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the liver, nasal cavity, trachea, lung and esophagus. |
In vivo | Mice with N-Nitrosodiethylamine (25mg/kg) intraperitonially resulted in fatty liver disease leading to progress of cancer disease. |
別名 | Diethylnitrosamine, NDEA |
分子量 | 102.14 |
分子式 | C4H10N2O |
CAS No. | 55-18-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 98 mg/mL (959.47 mM), Sonication is recommended.
DMSO: 50 mg/mL (489.52 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
N-Nitrosodiethylamine 55-18-5 Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA/RNA Synthesis Inhibitor Diethylnitrosamine N Nitrosodiethylamine inhibit NNitrosodiethylamine NDEA inhibitor