Powder: -20°C for 3 years | In solvent: -80°C for 1 year
p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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10 mg | 在庫あり | ¥ 8,000 | |||
25 mg | 在庫あり | ¥ 13,000 | |||
50 mg | 在庫あり | ¥ 18,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 20,500 |
説明 | p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM. |
ターゲット&IC50 | TPH:ki:32.6 μM , TPH:32.6 μM (Ki) |
In vivo | 4-Ethynyl-L-phenylalanine (30 mg/kg; i.p.) decreases in 5-HT and 5-HIAA levels in the rat midbrain but not in tissue. It is not inhibiting the aromatic amino acid decarboxylase. It has a low affinity for various recombinant 5-HT receptors. |
別名 | 4-Ethynyl-L-phenylalanine |
分子量 | 189.21 |
分子式 | C11H11NO2 |
CAS No. | 278605-15-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1M HCl: 1M HCl : 216.0 mg/mL (1141.6 mM), when pH is adjusted to 1 with HCl. Sonication is recommended.
DMSO: 2.0 mg/mL (10.6 mM), Sonication is recommended.
1M NaOH: 216.0 mg/mL (1141.6 mM), when pH is adjusted to 11 with NaOH. Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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p-Ethynylphenylalanine 278605-15-5 Metabolism Others Hydroxylase 4-Ethynyl-L-phenylalanine Inhibitor inhibitor inhibit