Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PKM2 activator 2 is a pyruvate kinase M2 (PKM2) activator with an AC 50 value of 66 nM.PKM2 activator 2 has anti-tumor proliferative properties and attenuates the Warburg effect by normalizing cellular glycolytic metabolism through activation of PKM2.
説明 | PKM2 activator 2 is a pyruvate kinase M2 (PKM2) activator with an AC 50 value of 66 nM.PKM2 activator 2 has anti-tumor proliferative properties and attenuates the Warburg effect by normalizing cellular glycolytic metabolism through activation of PKM2. |
ターゲット&IC50 | PKM2:66 nM (EC50) |
In vitro | PKM2 activator 2 (compound 28) is a highly potent activator, activates pyruvate kinase with an AC50 value of 66 nM in the luciferase-coupled assay.[1] |
分子量 | 452.49 |
分子式 | C20H18F2N2O4S2 |
CAS No. | 1186660-06-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.5 mg/mL (9.9 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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PKM2 activator 2 1186660-06-9 Metabolism PKM Inhibitor inhibitor inhibit