Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 19,000 | |||
5 mg | 在庫あり | ¥ 45,500 | |||
10 mg | 在庫あり | ¥ 68,000 | |||
25 mg | 在庫あり | ¥ 114,000 | |||
50 mg | 在庫あり | ¥ 165,000 | |||
100 mg | 在庫あり | ¥ 226,500 | |||
500 mg | 在庫あり | ¥ 454,500 |
説明 | PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells. |
ターゲット&IC50 | PRMT6:192 nM |
In vitro |
PRMT6-IN-3 (compound 25) (0-40 μM; 72 h) significantly induces apoptosis of cancer cells in a dose-dependent manner. Among them, a concentration of 40 μM could induce apoptosis in 43.44% and 35.08% of HCC827 and MDA-MB-435 cells, respectively.[1] PRMT6-IN-3 (80 μM; 3-7 days) has anti-proliferative activity against HCC827 and MDA-MB-435 cells.[1] |
分子量 | 374.5 |
分子式 | C19H26N4O2S |
CAS No. | 2890765-10-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (146.86 mM)
You can also refer to dose conversion for different animals. 詳細
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PRMT6-IN-3 2890765-10-1 Apoptosis Chromatin/Epigenetic Histone Methyltransferase Inhibitor inhibitor inhibit