keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Semaglutide Acetate is an agonist of a glucagon-like peptide 1 (GLP-1) receptor and can be used in studies about the treatment of type 2 diabetes.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 55,000 |
5 mg | 在庫あり | ¥ 114,500 |
10 mg | 在庫あり | ¥ 166,500 |
25 mg | 在庫あり | ¥ 259,500 |
50 mg | 在庫あり | ¥ 349,000 |
説明 | Semaglutide Acetate is an agonist of a glucagon-like peptide 1 (GLP-1) receptor and can be used in studies about the treatment of type 2 diabetes. |
In vitro | Semaglutide Acetate is a long-acting GLP-1 analogue with GLP-1 receptor affinity of 0.38 nM[3]. |
In vivo | Semaglutide Acetate improves 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced motor impairments. Semaglutide Acetate rescues the decrease of tyrosine hydroxylase (TH) levels, reduces lipid peroxidation, inhibits the apoptosis pathway, alleviates the inflammation response, increases autophagy-related protein expression, and protects dopaminergic neurons in the substantia nigra and striatum[2]. In mini-pigs, The plasma half-life of Semaglutide Acetate (i.v.) is 46h and the MRT of Semaglutide Acetate (s.c.) is 63.6h[3]. |
別名 | Semaglutide Acetate(910463-68-2 Free base) |
分子量 | 4174.68 |
分子式 | C189H295N45O61 |
CAS No. | 1997361-85-9 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: <0.05 mg/mL (insoluble)
DMSO: 4.17 mg/mL (1 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Semaglutide Acetate 1997361-85-9 GPCR/G Protein Glucagon Receptor Semaglutide Acetate(910463-68-2 Free base) Inhibitor inhibitor inhibit