Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 11,000 | |||
5 mg | 在庫あり | ¥ 33,000 | |||
10 mg | 在庫あり | ¥ 57,500 | |||
25 mg | 在庫あり | ¥ 97,500 | |||
50 mg | 在庫あり | お問い合わせ |
説明 | GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor). |
In vitro | GLP-1R Agonist DMB inhibits forskolin-induced cAMP accumulation in BHK cells expressing the recombinant human receptor with an EC50 value of 101 nM. GLP-1R Agonist DMB (100 and 1,000 nM) increases insulin levels induced by D-(+)-glucose in pancreatic islets isolated from wild-type, but not Glp1r knockout, mice[1]. |
In vivo | GLP-1R Agonist DMB reduces fasting plasma glucose levels in mice when administered at a dose of 5 μmol/kg[1]. |
分子量 | 348.25 |
分子式 | C13H15Cl2N3O2S |
CAS No. | 281209-71-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9mg/mL (25.8mM)
You can also refer to dose conversion for different animals. 詳細
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GLP-1R Agonist DMB 281209-71-0 GPCR/G Protein Glucagon Receptor GLP1R Agonist DMB GLP 1R Agonist DMB Inhibitor inhibitor inhibit