Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SMTIN-T140 (compound 6a), a potent TRAP1 (tumor-necrosis-factor-receptor associated protein 1) inhibitor with an IC50 of 1.646 μM, exhibits anticancer activity by inducing mitochondrial dysfunction, elevating mitochondrial ROS production, and activating AMPK. Notably, SMTIN-T140 effectively suppressed tumor growth without discernible in vivo toxicity in a PC3 prostate cancer cell-xenografted mouse model [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | SMTIN-T140 (compound 6a), a potent TRAP1 (tumor-necrosis-factor-receptor associated protein 1) inhibitor with an IC50 of 1.646 μM, exhibits anticancer activity by inducing mitochondrial dysfunction, elevating mitochondrial ROS production, and activating AMPK. Notably, SMTIN-T140 effectively suppressed tumor growth without discernible in vivo toxicity in a PC3 prostate cancer cell-xenografted mouse model [1]. |
分子量 | 718.02 |
分子式 | C36H34BrClFN5OP+ |
CAS No. | 2851532-40-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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SMTIN-T140 2851532-40-4 Cytoskeletal Signaling Metabolism HSP Inhibitor inhibitor inhibit