store at low temperature
store at -20°C
Tafasitamab (XmAb5574) is an FC-modified humanized monoclonal antibody targeting the human B-cell surface antigen CD19 for the study of diffuse large B-cell lymphoma.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 98,500 |
5 mg | 在庫あり | ¥ 314,500 |
10 mg | 在庫あり | ¥ 424,500 |
25 mg | 在庫あり | ¥ 626,500 |
50 mg | 在庫あり | ¥ 844,500 |
100 mg | 在庫あり | ¥ 1,124,500 |
説明 | Tafasitamab (XmAb5574) is an FC-modified humanized monoclonal antibody targeting the human B-cell surface antigen CD19 for the study of diffuse large B-cell lymphoma. |
In vitro | In an E/T ratio-dependent manner, tafasitamab (XmAb5574) induced cytotoxicity to Mino and Jeko (MCL) cell lines. It also increased antibody-dependent cellular phagocytosis (ADCP) and antiproliferative activity. Additionally, tafasitamab (XmAb5574) can enhance the anti-proliferative activity induced by caspase-mediated apoptosis[1][2]. |
In vivo | In a xenograft tumor model of disseminated BL mice, tafasitamab (2.5 μg/kg, once on day 1) inhibited lymphoma growth[1]. |
別名 | MOR00208, XmAb5574, Tafasitamab-cxix |
分子量 | N/A |
CAS No. | 1422527-84-1 |
store at low temperature
store at -20°C
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Tafasitamab 1422527-84-1 Apoptosis Immunology/Inflammation Immunology/Inflammation related MOR 00208 MOR-00208 MOR00208 XmAb5574 Tafasitamab-cxix Inhibitor inhibitor inhibit