Powder: -20°C for 3 years | In solvent: -80°C for 1 year
USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D. USP8-IN-2 is a potential compound for the treatment of cancer and viral infections.
説明 | USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D. USP8-IN-2 is a potential compound for the treatment of cancer and viral infections. |
In vitro | USP8-IN-3 inhibits the proliferation of H1957 cells, with a GI50 of 24.93 μM[1]. |
分子量 | 444.9 |
分子式 | C19H20ClF3N4OS |
CAS No. | 2477651-11-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (61.81 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
USP8-IN-2 2477651-11-7 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB Inhibitor inhibitor inhibit