store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Verosudil (AR-12286) is a highly potent Rho kinase (ROCK) inhibitor with a Ki of 2 and 2 nM against ROCK1 and ROCK2, respectively. AR-12286 reverses steroid-induced intraocular pressure in mice by decreasing intraocular pressure by increasing outflow of aqueous ether through the trabecular reticulum.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 60,500 | |||
10 mg | 在庫あり | ¥ 98,500 | |||
25 mg | 在庫あり | ¥ 157,500 | |||
50 mg | 在庫あり | ¥ 222,500 | |||
100 mg | 在庫あり | ¥ 294,000 | |||
500 mg | 在庫あり | ¥ 601,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 67,500 |
説明 | Verosudil (AR-12286) is a highly potent Rho kinase (ROCK) inhibitor with a Ki of 2 and 2 nM against ROCK1 and ROCK2, respectively. AR-12286 reverses steroid-induced intraocular pressure in mice by decreasing intraocular pressure by increasing outflow of aqueous ether through the trabecular reticulum. |
ターゲット&IC50 | CAM2A:5855 nM (Ki), MRCKA:28 nM (Ki), ROCK1:2 nM (Ki), PKA:69 nM (Ki), PKC theta:9322 nM (Ki), ROCK2:2 nM (Ki) |
別名 | AR-12286 |
分子量 | 327.4 |
分子式 | C17H17N3O2S |
CAS No. | 1414854-42-4 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (30.54 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Verosudil 1414854-42-4 Cell Cycle/Checkpoint Cytoskeletal Signaling Stem Cells ROCK AR12286 AR 12286 AR-12286 Inhibitor inhibitor inhibit